Multiple sets of multiples

Written by Carissa Mason, with input from Shaie O’Brien, Australian Twin Registry

New South Wales mum Caromy McLean was still breastfeeding her first set of twins when she found out she was pregnant with a second set. “I had four in nappies for a year”, Caromy says.

MORE >> Are you ready for twins again?

How genes are expressed differently without changes to DNA

Written by Assoc Prof Mark Umstad, Obstetrician & Gynaecologist, and AMBA Patron

Classic twin studies compare similarities between monozygotic (identical) and dizygotic (fraternal) twins. For any condition in which monozygotic twins are more similar than dizygotic twins, there is an implication that there is a more significant genetic than environmental influence. Because twins share many aspects of their environment including the uterus, parents, home and schooling, differences can be assessed in relation to how similar their genes are. In recent years, it has been recognised that there is more to this “nature versus nurture” concept. This is where epigenetics has developed.

MORE >> Epigenetics and twins

A multiple pregnancy is usually a contraindication to a VBAC 

Written by Assoc Prof Mark Umstad, AMBA Patron, and published in the AMBA Magazine

The rate of caesarean section has steadily increased in Australia over the past few decades. The caesarean section rate is now around 30% for singleton pregnancies, around 70% for twin pregnancies and virtually 100% for triplet and higher order multiple pregnancies.

MORE >> Vaginal birth after caesarean section